Discrimination for medical mortality throughout the adjusted logistic regression model was modestly higher for the SF-TAR (AUROC = 0

Discrimination for medical mortality throughout the adjusted logistic regression model was modestly higher for the SF-TAR (AUROC = 0

A total of 86.1% of patients had at least 1 PaO2/FiO2 ratio during the first 24 hours of ventilation (Supplemental Table 2 a ). 81, 95% CI = 0.81-0.82) than with the worst PaO2/FiO2 ratio (AUROC = 0.78, 95% CI = 0.78-0.79, p < 0.001). Results were similar when SF-TAR was compared with the single worst SpO2/FiO2 ratio in the first 24 hours (AUROC = 0.79; 95% CI = 0.79-0.80, p < 0.01). Even when SF-TAR data were limited to either the first 6 or 12 hours of mechanical ventilation, the AUCs for these models were both 0.80 (95% CI = 0.79-0.80 and 0.80-0.81, respectively). Each 10% increase in SF-TAR during the first 24 hours of ventilation was associated with a 24% increase in the odds of hospital mortality (adjusted odds ratio = 1.24, 95% CI = 1.23-1.26, p < 0.001).

Recognition Studies

The MIMIC cohort included 13,755 hospitalizations with mechanical ventilation.

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